What question did this study set out to answer?

To determine whether selective screening and treatment for cervical Chlamydia trachomatis infection prevents pelvic inflammatory disease in high-risk women.

May 23, 1996New England Journal of Medicine

Prevention of Pelvic Inflammatory Disease by Screening for Cervical Chlamydial Infection

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To determine whether selective screening and treatment for cervical Chlamydia trachomatis infection prevents pelvic inflammatory disease in high-risk women.
Randomized controlled trial of 2607 high-risk women aged 18 to 34 years identified through a questionnaire mailed to health maintenance organization enrollees.
Eligible participants were randomly assigned to selective screening for C. trachomatis (n=1009) or usual care (n=1598) and monitored for one year.
Confirmed pelvic inflammatory disease cases were evaluated using an intention-to-screen analysis and adjusted using logistic regression.
In the screening arm, 64% of women (645/1009) underwent testing, with 7% testing positive and receiving treatment.
At one-year follow-up, verified pelvic inflammatory disease occurred in 9 women in the screening group versus 33 women in the usual care group (RR, 0.44; 95% CI, 0.20 to 0.90).

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Implication

Randomized trial demonstrates reduced pelvic inflammatory disease incidence in high-risk women screened for chlamydia, indicating the clinical benefit of selective testing.

Cite This Study

Scholes et al. (1996) studied this question.

synapsesocial.com/papers/6a1d108f102421609404cc0e https://doi.org/10.1056/nejm199605233342103

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Implication

Randomized trial demonstrates reduced pelvic inflammatory disease incidence in high-risk women screened for chlamydia, indicating the clinical benefit of selective testing.

Prevention of Pelvic Inflammatory Disease by Screening for Cervical Chlamydial Infection

Key Points

Discussion

Implication

Cite This Study

Prevention of Pelvic Inflammatory Disease by Screening for Cervical Chlamydial Infection

Key Points

Discussion

Implication

Cite This Study

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