Why the study?
Does vaccinia virus vaccination generate virus-specific cytotoxic activity by human peripheral lymphocytes?
Does vaccinia virus vaccination generate virus-specific cytotoxic activity by human peripheral lymphocytes?
Vaccinia virus vaccination induces specific anti-viral antibody and K cell-mediated antibody-dependent cell cytotoxicity, suggesting ADCC is important in human recovery from viral infections.
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Suggests ADCC may aid antiviral recovery in humans; leaves open its clinical relevance and requires prospective confirmation.
Perrin et al. (1977) studied this question.
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