Population
Hamster cheek pouch model
Comparison
Alteration of suffusion solution Po2 vs Lower suffusion solution Po2 (11 mm Hg)
Design
Preclinical
Authors
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May inform microvascular oxygen sensing; leaves open translation to human physiology or clinical oxygen use.
Increases in oxygen tension lead to arteriolar constriction in the hamster cheek pouch, though the response of large and small arterioles does not appear to be mediated by a direct effect of oxygen on vascular smooth muscle.
Brian R. Duling (1972) studied this question.
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