Why the study?
The burden of non-communicable diseases has increased in South Africa, with diabetes mellitus and hypertension being the two most prevalent conditions linked to rapidly rising mortality.
What are the socio-demographic and modifiable risk factors associated with diabetes mellitus and hypertension among resource-constrained patients from rural areas in South Africa?
What are the socio-demographic and modifiable risk factors associated with diabetes mellitus and hypertension among resource-constrained patients from rural areas in South Africa?
In a resource-constrained South African population, diabetes was significantly associated with smoking, salt intake, and dyslipidemia, while hypertension was strongly associated with increased BMI, highlighting key targets for lifestyle intervention.
Identifies modifiable DM/HTN factors in rural South Africa; cross-sectional data leave causality open for prospective studies.
BACKGROUND: Recently, developing countries have shown a dramatic increase in non-communicable diseases (NCDs). The burden of NCDs in South Africa has increased over the past years resulting in an estimated 37% of all- cause mortality and 16% of disability-adjusted life years. Currently, diabetes mellitus (DM) and hypertension (HTN) are the two most prevalent NCDs associated with the rapid increase in mortality. OBJECTIVE: To demonstrate the socio-demographic and modifiable risk factors of diabetes mellitus (DM) and hypertension (HTN) among South African adults. METHODS: A cross-sectional analytical study was conducted in the Cecilia Makiwane Hospital serving the residents of Mdantsane. Relevant socio-demographic data, anthropometric measurements, triplicate blood pressure, fasting blood glucose and lipogram analysis were obtained from 265 outpatients. RESULTS: Multivariate anlysis shows that; salt intake, smoking, elevated triglycerides and decreased high-density lipoprotein levels were significantly associated with DM with adjusted odds ratio of 0.18 (p=0.002), 0.26 (p=0.048), 2.19 (p=0.006) and 0.38 (p=0.001), respectively. Overweight and obesity were significantly associated with hypertension with odds ratio of 0.03 (p=0.01) and 0.06 (p=0.006), respectively. CONCLUSION: The burden of DM and HTN on society can be drastically reduced with simple lifestyle changes, development of preventative strategies, large-scale screening and better disease management in South Africa.
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Xhakaza et al. (2020) studied this question.
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