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June 1, 2026Frontiers in Surgery0 citationsOpen Access

Case Report: Bioresorbable implant in anterior abdominal wall reconstruction in women of reproductive age. Case Report with pregnancy and a 10-year follow-up

MPMichał PutkoMZMateusz ZamkowskiMŚMaciej Śmietański

Key Points

  • This case report aims to evaluate the safety and long-term efficacy of a bioresorbable mesh for abdominal wall reconstruction in a woman who later became pregnant.
  • Presented a case of a 42-year-old woman with abdominal wall hernia repaired with P4HB mesh.
  • Monitored patient through a subsequent pregnancy and assessed long-term outcomes including hernia recurrence.
  • Conducted follow-up at 10 years with ultrasonography and laparoscopic inspection.
  • Pregnancy and delivery were uneventful, with no abdominal wall-related symptoms reported during or after.
  • At 10-year follow-up, no hernia recurrence was noted, and complete resorption of the mesh was confirmed during inspection.
  • Integrity of the linea alba was preserved, suggesting favorable outcomes from using the bioresorbable mesh.

Abstract

Introduction Surgical management of anterior abdominal wall hernias in women of reproductive age remains challenging, as repair techniques must accommodate physiological changes during pregnancy. While permanent synthetic meshes are effective, concerns exist regarding their mechanical behavior in the context of pregnancy in this patient population. Bioresorbable implants have emerged as a potential alternative; however, clinical data on pregnancy outcomes remain limited. Aim To present a case of abdominal wall reconstruction using a bioresorbable poly-4-hydroxybutyrate (P4HB, Phasix®) mesh with subsequent pregnancy and long-term follow-up. Case description A 42-year-old woman with a history of recurrent linea alba hernia and diastasis underwent retromuscular repair using a P4HB mesh. Sixteen months later, she conceived. Pregnancy and delivery were uneventful, with no abdominal wall-related symptoms. At 10-year follow-up, ultrasonography demonstrated no hernia recurrence, and laparoscopic inspection confirmed complete mesh resorption with preserved integrity of the linea alba. Conclusions In this case, the use of a bioresorbable P4HB mesh was associated with an uncomplicated pregnancy and durable long-term outcome. However, given the single-case design and small defect size, these findings should be interpreted with caution and require confirmation in larger studies.

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Cite This Study

Putko et al. (2026) studied this question.

synapsesocial.com/papers/6a1d20bc02fbce9130637058https://doi.org/10.3389/fsurg.2026.1776962
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