Retrospective analysis shows no increase in seizures after changing antiepileptic drug guidelines in neurosurgery, suggesting safety of new protocol.
• Postoperative seizure incidence after supratentorial craniotomy was 5.5%. • Stopping prophylactic antiepileptic drugs did not increase seizure incidence. • One-month functional autonomy and lifestyle outcomes were similar between groups. • Adverse events related to antiepileptic drugs occurred in 1.5% of patients.
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Jarno et al. (2026) studied this question.
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