Why the study?
Does permanent atrial pacing improve symptoms and cardiac output compared to chronic ventricular pacing in patients with symptomatic sinus bradycardia and ventriculo-atrial conduction?
Does permanent atrial pacing improve symptoms and cardiac output compared to chronic ventricular pacing in patients with symptomatic sinus bradycardia and ventriculo-atrial conduction?
In patients with sick sinus syndrome and ventriculo-atrial conduction, upgrading from ventricular to atrial pacing resolves pacemaker syndrome symptoms and improves cardiac output.
May support atrial pacing upgrade in pacemaker syndrome; leaves open need for prospective trials.
Three patients with symptomatic sinus bradycardia due to sick sinus syndrome were treated with permanent ventricular pacing for periods ranging from 2.5 to 4 years. All three patients had ventriculo-atrial conduction on routine electrocardiography. Although ventricular pacing was effective, they complained of fatigue, lightheadedness, and near syncope. Hemodynamic studies revealed the presence of regular cannon waves in the right atrium as well as in the pulmonary artery wedge pressure curves. Temporary atrial pacing resulted in disappearance of the cannon waves and a significant rise in cardiac output (32-48%). After normal atrio-ventricular conduction was confirmed by rapid atrial stimulation and His bundle electrocardiography, the pacing mode was changed to permanent atrial pacing on demand. The effort tolerance of the patients markedly improved, and the previously mentioned symptoms disappeared. Control hemodynamic studies 9 to 12 months after implantation of the atrial demand pacemaker showed that the improvement in cardiac performance was maintained.
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GAMAL et al. (1981) studied this question.
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