Key result
Single chamber atrial pacing maintains ~75% mode survival over a decade in sinus node disease.
Why the study?
Many centers limit use of atrial pacing in sinus node disease due to concerns about future AV block or atrial fibrillation, despite potential benefits over right ventricular stimulation.
Does single chamber atrial pacing provide safe long-term outcomes in patients with sinus node disease?
Population
213 patients with sinus node disease
Comparison
Patients with brady-tachy syndrome vs bradycardia only; survival compared to age and gender-matched general Swedish population
Design
Long-term cohort study
Follow-up
Mean 10.1 years, up to 19 years
Authors
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Supports atrial pacing durability in sinus node disease; leaves open randomized confirmation of long-term safety.
Cohort (n=213)
Does single chamber atrial pacing provide safe long-term outcomes in patients with sinus node disease?
Single chamber atrial pacing is a safe and reliable long-term option for patients with sinus node disease, with a low annual incidence of high-grade AV block.
Höijer et al. (2007) conducted a cohort in Sinus node disease (n=213). Single chamber atrial pacing vs. Age and gender-matched general population / patients with bradycardia only was evaluated on Survival, development of atrial fibrillation and AV block, and total mode survival. Single chamber atrial pacing in patients with sinus node disease resulted in 75% overall mode survival at a mean follow-up of 10.1 years, with a 1.8% annual incidence of high-grade AV block.
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