On the Specificity of the G Abnormality in Human Meningomas Studied by the Fluorescence Technique

The chromosomes were studied in eight human meningomas using the fluorescence technique. Five tumours had a hypodiploid stemline with the loss of 1 No. 22, two tumours had a pseudodiploid stemline with a structurally changed G22, and one tumour had a normal stemline but contained variant cells with the loss of one G22. The results were in accordance with previous preliminary observations and demonstrated that there was a specific G pattern in the human meningomas. This G pattern was compared with that found in chronic myeloic leukaemia in man, and the similarities were proposed to be due to basic progressional mechanisms.