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This study evaluates the relationship between HbA1c levels and inflammatory markers in individuals with type 2 diabetes mellitus.

Association of HbA1c levels with neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and platelet-to-lymphocyte ratio in patients with diabetes mellitus: a case–control study

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This study evaluates the relationship between HbA1c levels and inflammatory markers in individuals with type 2 diabetes mellitus.
Retrospective case-control study including 138 patients with T2DM and 118 healthy controls.
Compared HbA1c, WBC count, NLR, MLR, and PLR at baseline and follow-up visits.
Conducted correlation analysis for diabetes duration, glucose, and HbA1c levels with inflammatory markers.
HbA1c levels significantly higher in uncontrolled diabetes group (p < 0.001).
Positive correlations between NLR, MLR, and HbA1c levels (r = 0.316–0.354, p < 0.001).
Changes in NLR and PLR levels observed at follow-up (p < 0.05), while MLR change was not significant (p = 0.083).

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Case–control study evaluates associations between HbA1c and inflammatory markers in diabetes, indicating clinical relevance.

Kahvecioglu et al. (2026) studied this question.

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