Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
June 1, 2026Gastroenterology Research and PracticeOpen Access

High Prevalence of Sarcopenia in Noncirrhotic Women With Primary Biliary Cholangitis: A Comparative Study of Clinical Characteristics and Risk Factors

View Full Paper
Ask AI
Bookmark
Share

Authors

JZJingyi ZhangJXJiamin XuWBWeimin Bao

Discussion

Loading...

Member takes

Overview

Comparative study reveals high sarcopenia prevalence in noncirrhotic women with PBC, suggesting new screening needs.

Key Points

  • This research investigates the prevalence and risk factors of sarcopenia in women with primary biliary cholangitis.
  • Enrolled 229 female patients with chronic hepatitis B and PBC.
  • Skeletal muscle area assessed via abdominal CT, and sarcopenia defined using skeletal muscle index.
  • Compared prevalence of sarcopenia between PBC and chronic hepatitis B patients.
  • Sarcopenia prevalence was significantly higher in noncirrhotic PBC patients (75.60%) compared to noncirrhotic CHB patients (31.30%), p < 0.001.
  • Cirrhotic PBC and CHB patients showed no significant difference in sarcopenia prevalence.
  • Low BMI (OR = 1.342) and osteopenia/osteoporosis (OR = 4.2) were identified as independent risk factors for sarcopenia in PBC patients.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a1d22f702fbce9130638a55https://doi.org/10.1155/grp/8688776
View Full Paper
Ask AI
Bookmark
Share