What does this research mean for the field?

Copper nanoparticles green synthesized using Conocarpus erectus L. reduce Toxoplasma gondii tachyzoites in vitro and increase the survival time of infected mice in vivo. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to evaluate the anti-Toxoplasma effects of copper nanoparticles synthesized from Conocarpus erectus L. using both in vitro and in vivo methods.

June 1, 2026Advanced Biomedical ResearchOpen Access

Anti-Toxoplasma Activity of Copper Nanoparticles (CuNPs) Synthesized Using Conocarpus erectus L.: An In Vitro and In Vivo Study

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Authors

BRBahram RostamiMedical University of Ilam HHHamid HasanpourMedical University of Ilam SAS Jafar pour AzamiTehran University of Medical Sciences

Discussion

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Implication

Randomized trial evaluates anti-Toxoplasma activity of copper nanoparticles in mice, indicating potential as supplementary treatment.

Key Points

This research aims to evaluate the anti-Toxoplasma effects of copper nanoparticles synthesized from Conocarpus erectus L. using both in vitro and in vivo methods.
Copper nanoparticles were synthesized using the aqueous extract of Conocarpus erectus L.
An MTT assay assessed cell viability against Toxoplasma gondii tachyzoites at various concentrations and exposure times.
In vivo tests involved infecting BALB/c mice with Toxoplasma followed by CuNP treatment and comparison with controls.
CuNPs had a particle size of less than 20 nm, with a maximum peak at 315 nm.
The highest mortality rate of Toxoplasma gondii was observed at 160 ppm concentration after 8 hours of CuNP exposure.
Oral administration of CuNPs increased mice survival time and reduced parasitemia compared to the control group.

Cite This Study

Rostami et al. (2026) studied this question.

synapsesocial.com/papers/6a1d22f702fbce9130638a5d https://doi.org/10.4103/abr.abr_401_23

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June 1, 2026Advanced Biomedical ResearchOpen Access

Anti-Toxoplasma Activity of Copper Nanoparticles (CuNPs) Synthesized Using Conocarpus erectus L.: An In Vitro and In Vivo Study

View Full Paper

Ask AI

Bookmark

Authors

BRBahram RostamiMedical University of Ilam HHHamid HasanpourMedical University of Ilam SAS Jafar pour AzamiTehran University of Medical Sciences

Discussion

Member takes

Implication

Randomized trial evaluates anti-Toxoplasma activity of copper nanoparticles in mice, indicating potential as supplementary treatment.

Key Points

This research aims to evaluate the anti-Toxoplasma effects of copper nanoparticles synthesized from Conocarpus erectus L. using both in vitro and in vivo methods.
Copper nanoparticles were synthesized using the aqueous extract of Conocarpus erectus L.
An MTT assay assessed cell viability against Toxoplasma gondii tachyzoites at various concentrations and exposure times.
In vivo tests involved infecting BALB/c mice with Toxoplasma followed by CuNP treatment and comparison with controls.
CuNPs had a particle size of less than 20 nm, with a maximum peak at 315 nm.
The highest mortality rate of Toxoplasma gondii was observed at 160 ppm concentration after 8 hours of CuNP exposure.
Oral administration of CuNPs increased mice survival time and reduced parasitemia compared to the control group.

Cite This Study

Rostami et al. (2026) studied this question.

synapsesocial.com/papers/6a1d22f702fbce9130638a5d https://doi.org/10.4103/abr.abr_401_23

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

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