What does this research mean for the field?

Endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) is an accurate and safe method for assessing portal hypertension that correlates strongly with direct transjugular measurements, though the presence of portal vein thrombosis may cause discrepancies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to compare EUS-guided portal pressure gradient with direct measurements during TIPS placement in patients with portal hypertension.

June 1, 2026Gastroenterology reportOpen Access

Endoscopic ultrasound versus direct transjugular portal pressure gradient in patients receiving TIPS: influence of portal vein thrombosis

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This study aims to compare EUS-guided portal pressure gradient with direct measurements during TIPS placement in patients with portal hypertension.
Consecutive patients scheduled for TIPS between March 2023 and December 2024 were included.
EUS was performed using a 22-gauge FNA needle attached to an invasive pressure monitoring module.
Technical success rates for EUS-PPG and HVPG were recorded.
Technical success rates for EUS-PPG and HVPG were 92.3% and 100%, respectively.
Strong correlation observed between EUS-PPG and T-PPG (r = 0.88, P < 0.01) and moderate correlation between EUS-PPG and HVPG (r = 0.58, P < 0.05).
Presence of portal vein thrombosis was associated with a ≥ 3 mmHg difference between EUS-PPG and T-PPG (P = 0.04).

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Implication

Randomized trial compares endoscopic ultrasound and direct pressure measurements in patients with portal hypertension, suggesting improved assessment reliability.

Cite This Study

Dragomir et al. (2026) studied this question.

synapsesocial.com/papers/6a1d22f702fbce9130638b34 https://doi.org/10.1093/gastro/goag052

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Implication

Randomized trial compares endoscopic ultrasound and direct pressure measurements in patients with portal hypertension, suggesting improved assessment reliability.

Endoscopic ultrasound versus direct transjugular portal pressure gradient in patients receiving TIPS: influence of portal vein thrombosis

Key Points

Discussion

Implication

Cite This Study

Endoscopic ultrasound versus direct transjugular portal pressure gradient in patients receiving TIPS: influence of portal vein thrombosis

Key Points

Discussion

Implication

Cite This Study

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