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June 1, 2026Open Access

Formulation and Evaluation of Curcumin-Loaded Microsphere for Targeted Therapy of Colon Cancer

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Authors

SNSayali H. Dherange1, Anil B. Panchal2*, Sampat D. Navale3

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Implication

Randomized trial evaluates microspheres’ effectiveness in targeting colon cancer, suggesting improved treatment options.

Key Points

  • This research aims to develop curcumin-loaded microspheres to enhance the therapeutic potential of curcumin in colon cancer treatment.
  • Formulated microspheres using ethyl cellulose and a 1:2 drug-to-polymer ratio.
  • Utilized emulsion solvent evaporation technique with a stirring speed of 1000 rpm.
  • Evaluated microspheres for particle size, surface morphology, encapsulation efficiency, and drug loading capacity.
  • In vitro release studies showed a gradual curcumin release over time.
  • Stability studies confirmed curcumin's protection from degradation.
  • Microspheres improved curcumin's bioavailability and therapeutic effectiveness.

Cite This Study

Sayali H. Dherange1, Anil B. Panchal2*, Sampat D. Navale3 (2026) studied this question.

synapsesocial.com/papers/6a1d234302fbce9130638ed9https://doi.org/10.5281/zenodo.20458200
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  5. 5Formulation and In Vitro Characterisation of Chitosan-Alginate Nanoparticles Loaded with Curcumin for Targeted Colon Cancer Drug Delivery: Effect of Polymer Ratio on Encapsulation Efficiency, Release Kinetics, and Cytotoxicity2026