Is there an Association between Vitamin D Status and Left Ventricular Ejection Fraction

Background and aim: Some recent studies have shown that vitamin D deficiency was a common finding in patients with cardiovascular disease. Because of the high prevalence of cardiovascular disease and vitamin D deficiency in Iranian population, we examined the correlation between vitamin D blood levels and patients with heart failure (HF). Material and Methods: This analytical cross-sectional study was performed using a randomized sampling technique. One hundred forty-five patients who were admitted to hospitals in Tehran from November 2021 to April 2022 participated in this study. Descriptive analysis and inference tests, including chi-square and t-test were used. Logistic regression tests were also used to find the correlations between variables. A P value less than 0.05 was considered for statistical significance. Results: In aggregate, 145 patients with an average age of 59.91 ± 10.75 years were studied. The average amount of vitamin D was 13.3 ± 12.8 ng/ml. This average was 15.0 ±14.2 ng/ml in patients with normal ejection fraction (EF), 14.6 ± 12.9 ng/ml in patients with mild severity EF, 14.1 ± 11.8 ng/ml and 8.7 ± 5.6 ng/ml in moderate and severe severity EF respectively. (p=0.51) Discussion: Although, in our studies, low levels of serum vitamin D and diabetes were not significantly associated with EF, but preventing them is essential in mitigating risk factors in HF.