What does this research mean for the field?

Amoeboid movement and cytoplasmic streaming are driven by a calcium- and ATP-regulated contractile system composed of thick and thin filaments that are morphologically identical to myosin and actin found in vertebrate striated muscle. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

November 1, 1973The Journal of Cell BiologyOpen Access

The Contractile Basis of Amoeboid Movement

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Population

Cytoplasm isolated from single amoeba (Chaos carolinensis)

Design

Preclinical

Authors

DTD. Lansing TaylorUniversity of Pittsburgh JCJohn S. CondeelisAlbert Einstein College of Medicine PMPenny L. MooreNational Health Laboratory Service

Discussion

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Implication

Establishes calcium-ATP control of contractility in amoebae; leaves open extension to mammalian non-muscle cell motility.

Structured PICO

Population

Cytoplasm isolated from single amoeba (Chaos carolinensis)

Intervention

Manipulation of exogenous free calcium and ATP concentrations in physiological solutions

Outcome

Cytoplasmic contractility, viscoelasticity, and structural changes (thick and thin filaments)surrogate

The study demonstrates that amoeba cytoplasmic contractility is controlled by calcium and ATP, involving thick and thin filaments morphologically identical to those in vertebrate striated muscle.

Cite This Study

Taylor et al. (1973) studied this question.

synapsesocial.com/papers/6a1d27fe102421609404f048 https://doi.org/10.1083/jcb.59.2.378

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The Contractile Basis of Amoeboid Movement

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Contractile Basis of Amoeboid Movement

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider