Longitudinal Patterns of Blood Pressure, Incident Cardiovascular Events, and All-Cause Mortality in Normotensive Diabetic People
Why the study?
Does low blood pressure (<120/80 mm Hg) or a decline in blood pressure increase the risk of all-cause mortality or cardiovascular events in normotensive diabetic adults?
Population
3159 diabetic adults, free of hypertension, atherosclerotic cardiovascular diseases, or cancer at baseline
Comparison
Blood pressure <120/80 mm Hg or spontaneous… vs Blood pressure of 120 to 139/80 to 89 mm Hg
Design
Cohort
Follow-up
7 years
Authors
Discussion
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Member takes
Implication
Low BP signals higher mortality risk in normotensive diabetes; leaves open whether targets need revision.
Structured PICO
Does low blood pressure (<120/80 mm Hg) or a decline in blood pressure increase the risk of all-cause mortality or cardiovascular events in normotensive diabetic adults?
P
Population
3159 diabetic adults, free of hypertension, atherosclerotic cardiovascular diseases, or cancer at baseline
I
Intervention
Blood pressure <120/80 mm Hg or spontaneous decline in blood pressure
C
Comparator
Blood pressure of 120 to 139/80 to 89 mm Hg (stable)
O
Outcome
All-cause mortality and incident cardiovascular eventshard clinical
In normotensive diabetic individuals, low blood pressure (<120/80 mm Hg) or a spontaneous decline in BP is associated with increased all-cause mortality, while developing hypertension increases cardiovascular risk.
Cite This Study
Wu et al. (2016) studied this question.