Why the study?
Hematopoietic stem cell transplantation is associated with various cardiovascular complications, but the incidence and risk factors for short- and long-term cardiovascular events in contemporary adult recipients remained to be characterized.
What is the incidence of short-term and long-term cardiovascular events in adult patients undergoing hematopoietic stem cell transplantation?
Population
3,354 adult patients who underwent autologous or allogeneic HSCT
Comparison
Allogeneic vs autologous HSCT
Design
Multicenter observational study
Follow-up
Median 2.3 years
Authors
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May warrant enhanced CV monitoring post-HSCT; extends incidence estimates for allogeneic recipients but leaves open prevention strategies.
What is the incidence of short-term and long-term cardiovascular events in adult patients undergoing hematopoietic stem cell transplantation?
Hematopoietic stem cell transplantation is associated with a notable long-term risk of cardiovascular events, particularly atrial fibrillation and heart failure, with higher risks observed in allogeneic recipients and those with baseline cardiovascular comorbidities.
Vasbinder et al. (2023) studied this question.
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