What does this research mean for the field?

Small peptides, known as mimotopes, can successfully mimic functionally discontinuous epitopes of antigens to induce specific antibodies, providing a versatile platform for developing vaccines, diagnostics, and drugs. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

January 1, 2000Socio-Environmental Systems ModelingOpen Access

Mimotopes: realization of an unlikely concept

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Design

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Authors

RMRob H. MeloenPepscan (Netherlands)WPWouter C. PuijkPepscan (Netherlands)JSJerry W. SlootstraKiel University

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Implication

Mimotopes may enable new vaccine and diagnostic platforms; challenges prior assumptions against mimicking discontinuous epitopes.

Structured PICO

Intervention

Mimotopes (peptide mimics of epitopes)

Mimotopes represent a generic approach for developing vaccines, diagnostics, and drugs by mimicking receptor-ligand interactions.

Cite This Study

Meloen et al. (2000) studied this question.

synapsesocial.com/papers/6a1d2be573c56dd1bd2f4f6b https://doi.org/10.1002/1099-1352(200011/12)13:6<352::aid-jmr509>3.0.co;2-c

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Mimotopes: realization of an unlikely concept

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Mimotopes: realization of an unlikely concept

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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