Why the study?
Do non-antiarrhythmic agents improve the prevention of atrial fibrillation and maintenance of sinus rhythm in patients with atrial fibrillation?
Do non-antiarrhythmic agents improve the prevention of atrial fibrillation and maintenance of sinus rhythm in patients with atrial fibrillation?
This review summarizes the mechanisms and clinical evidence for using non-antiarrhythmic agents to prevent atrial fibrillation and maintain sinus rhythm.
Non-antiarrhythmic agents merit further evaluation for AF rhythm control; extends mechanistic evidence but leaves clinical adoption open.
This article reviews current evidence of non-antiarrhythmic agents for the prevention and maintenance of sinus rhythm in patients with atrial fibrillation. These nontraditional agents include angiotensin converting enzyme inhibitors, angiotensin receptor blockers, antiinflammatory agents, calcium channel blockers, and beta-blockers. The mechanisms of action and clinical trials regarding the effectiveness of these agents in atrial fibrillation prevention are reviewed.
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LALLY et al. (2007) studied this question.
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