The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients

Q: What does this research mean for the field?

Left ventricular hypertrophy and diastolic dysfunction do not independently predict initial hemorrhage volume, hematoma expansion, or poor short-term outcome in patients with deep intracerebral hemorrhage, despite an increased likelihood of developing intraventricular hemorrhage. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Karen C. Albright; J. Burak; Tiffany Chang; Aimee Aysenne; James E. Siegler; Laurie Schluter; Sharyl Martini; Amelia K. Boehme; Sheryl Martin‐Schild

doi:10.1155/2013/898163

August 19, 2013ISRN StrokeOpen Access

The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients

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Why the study?

Does the presence of LVH or DD predict initial ICH volume, hematoma expansion, or poor outcome in patients with supratentorial deep ICH?

Structured PICO

Does the presence of LVH or DD predict initial ICH volume, hematoma expansion, or poor outcome in patients with supratentorial deep ICH?

P

Population

Patients presenting with supratentorial deep intracerebral hemorrhage (ICH) from 7/2008 to 12/2010. Excluded: traumatic, lobar, infratentorial, secondary to elevated international normalized ratio, suspicious for underlying structural malformation, or where surgical evacuation was performed.

I

Intervention

Presence of left ventricular hypertrophy (LVH) or diastolic dysfunction (DD)

C

Comparator

Absence of LVH or DD

O

Outcome

Initial ICH volume, 33% hematoma volume expansion, and poor functional outcome

In patients with deep ICH, the presence of LVH or DD does not independently predict initial hemorrhage volume, hematoma expansion, or poor short-term functional outcome.

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Implication

Does not support LVH for ICH prognostication in deep hemorrhage; leaves open its role in other phenotypes or long-term outcomes.

Abstract

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Cite This Study

Albright et al. (2013) studied this question.

synapsesocial.com/papers/6a1d337d1c2cbcb15c5deedf https://doi.org/10.1155/2013/898163

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The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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