What question did this study set out to answer?

To determine whether intraventricular hemorrhage and intracerebral hemorrhage independently increase the risk of delayed cerebral ischemia following subarachnoid hemorrhage.

September 1, 2001Stroke

Effect of Cisternal and Ventricular Blood on Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage:

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Authors

JCJan ClaassenColumbia University Irving Medical Center GBGary L. BernardiniAlbany State University KKKurt T. KreiterQueens College, CUNY

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Implication

Observational cohort study reveals cisternal clot and lateral ventricular blood independently increase delayed cerebral ischemia risk after subarachnoid hemorrhage, indicating additive prognostic...

Key Points

To determine whether intraventricular hemorrhage and intracerebral hemorrhage independently increase the risk of delayed cerebral ischemia following subarachnoid hemorrhage.
Analyzed 276 consecutively admitted patients with subarachnoid hemorrhage who received an admission CT scan within 72 hours of symptom onset.
Quantified the volume and anatomical distribution of subarachnoid, intraventricular, and intracerebral blood on CT and evaluated their relationship with delayed cerebral ischemia using multiple logistic regression.
Delayed cerebral ischemia occurred in 20% of patients (54 of 276).
Thick subarachnoid clot completely filling any cistern or fissure (P=0.008; OR 2.3, 95% CI 1.5 to 9.5) and intraventricular hemorrhage in both lateral ventricles (P=0.001; OR 4.1, 95% CI 1.7 to 9.8) independently predicted delayed cerebral ischemia.
Additional independent predictors in the multivariate model included mean arterial pressure >112 mm Hg (OR 4.9, 95% CI 2.1 to 11.4) and transcranial Doppler mean velocity >140 cm/s within 5 days of hemorrhage (OR 3.8, 95% CI 1.5 to 9.5).

Cite This Study

Claassen et al. (2001) studied this question.

synapsesocial.com/papers/6a78a2c12e130d02afed3ef5 https://doi.org/10.1161/hs0901.095677

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Implication

Observational cohort study reveals cisternal clot and lateral ventricular blood independently increase delayed cerebral ischemia risk after subarachnoid hemorrhage, indicating additive prognostic...

Effect of Cisternal and Ventricular Blood on Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage:

Discussion

Member takes

Implication

Key Points

Cite This Study

Effect of Cisternal and Ventricular Blood on Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage:

Discussion

Member takes

Implication

Key Points

Cite This Study

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