Comparison of Beilstein CrossFirePlusReactions and the Selective Reaction Databases under ISIS

To answer the question “are small selective databases now redundant”, a comparison was made between the smaller, more selective reaction databases [under ISIS (Integrated Scientific Information System)] and a larger, more comprehensive database (Beilstein, via CrossFire) using references, exact reactions, named reactions, and transformations. The results show a large overlap of reference data with a smaller overlap of reaction data. Depending on the search, the overall view is that the databases are complementary.