What does this research mean for the field?

The pestivirus genome encodes a 7-kDa protein (p7) and a C-terminally extended form of E2 (E2p7) in the region between E2 and NS2-3, neither of which are major structural constituents of the virion. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 1996Journal of VirologyOpen Access

Processing in the pestivirus E2-NS2 region: identification of proteins p7 and E2p7

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Structured PICO

Population

Recombinant vaccinia viruses bearing C-terminally truncated E2-p?-NS2-encoding sequences derived from a bovine viral diarrhea virus (BVDV) strain, and BVDV and classical swine fever virus virions

Intervention

Expression studies and radiosequencing

Outcome

Identification of proteins p7 and E2p7 and determination of their structural role

Identifies the p7 and E2p7 proteins in the pestivirus genome and suggests they are not major structural constituents.

Discussion

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Implication

E2p7 and p7 are not major virion constituents; extends pestivirus polyprotein map but leaves open non-structural roles.

Cite This Study

Elbers et al. (1996) studied this question.

synapsesocial.com/papers/6a1d36cf750575be8d2f4a82 https://doi.org/10.1128/jvi.70.6.4131-4135.1996

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Processing in the pestivirus E2-NS2 region: identification of proteins p7 and E2p7

Structured PICO

Discussion

Implication

Cite This Study

Processing in the pestivirus E2-NS2 region: identification of proteins p7 and E2p7

Structured PICO

Discussion

Implication

Cite This Study

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