Why the study?
Does combined modality therapy (CHOP chemotherapy and consolidation radiation) improve survival in adults with mediastinal large cell lymphoma?
Does combined modality therapy (CHOP chemotherapy and consolidation radiation) improve survival in adults with mediastinal large cell lymphoma?
Combined modality therapy with CHOP and radiation achieves high remission rates in mediastinal large cell lymphoma, though bulky disease requires more aggressive treatment.
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May support combined modality therapy in mediastinal large cell lymphoma; leaves open randomized confirmation, especially for bulky disease.
Jacobson et al. (1988) studied this question.
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