Radiofrequency catheter ablation via a transseptal approach can successfully eliminate antegrade accessory pathway conduction in patients with WPW syndrome and permanent AF.
May support transseptal ablation during AF in WPW with permanent AF; hypothesis-generating, should not yet change practice.
The case of a 64-year-old man with Wolff-Parkinson-White syndrome and permanent atrial fibrillation (AF) is reported. The patient was admitted due to electrocardiographic feature of AF with rapid conduction over the left-sided accessory pathway. Administration of pirmenol effectively suppressed the ventricular response via an accessory pathway. A transesophageal echocardiography detected an uncertain thrombus in the left atrial appendage. During the 33-month follow-up period, the ventricular response via an accessory pathway was progressively facilitated. Radiofrequency catheter ablation using a transseptal approach was performed during AF, resulting in complete elimination of the antegrade accessory pathway conduction.
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Takahashi et al. (2005) studied this question.
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