Why the study?
Does heart rate reduction improve mortality and clinical outcomes in patients with cardiovascular disease?
Does heart rate reduction improve mortality and clinical outcomes in patients with cardiovascular disease?
Elevated heart rate is a marker of risk, and reducing it decreases cardiac metabolic demand, which has been shown to improve mortality in clinical studies.
Heart rate reduction with beta-blockers may improve outcomes in cardiovascular disease; supports consensus yet leaves optimal targets open for prospective trials.
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Roberto Ferrari (2003) studied this question.
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