Why the study?
Does early-onset familial obesity alter cardiac autonomic control as measured by heart period variability compared to healthy controls?
Population
20 young women, comprising 10 with early-onset familial obesity and 10 control subjects
Comparison
Early-onset familial obesity vs Non-obese control subjects
Design
Case-control
Authors
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Suggests autonomic imbalance in early-onset obesity; leaves open causal links to cardiovascular risk and need for prospective validation.
Does early-onset familial obesity alter cardiac autonomic control as measured by heart period variability compared to healthy controls?
Young women with early-onset familial obesity exhibit reduced ultra low and very low frequency power on 24-hour Holter monitoring, suggesting parasympathetic withdrawal that may contribute to increased cardiovascular risk.
Petretta et al. (1995) studied this question.
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