Why the study?
Do serum lipoproteins fluctuate during the normal menstrual cycle in young women?
Do serum lipoproteins fluctuate during the normal menstrual cycle in young women?
Serum HDL(2) levels fluctuate significantly during the normal menstrual cycle, peaking at ovulation.
Cycle-phase timing may influence HDL(2) measurements in young women; leaves open effects on CV risk assessment.
Lipoproteins were measured in sera from 11 young women having a similar environment and diet. Sera were obtained at weekly intervals over a 12-week period. The values of the lipoproteins during periods in the normal ovulatory cycle were compared to assess their relation to reported hormone concentrations in blood. 2. Only the 4-0s(f) (HDL(2)) (d 1.125 sodium chloride) fraction changed significantly; it increased at ovulation in ten of the 11 subjects and fell as menstruation approached. 3. There was greater variability in most of the low-density rather than the high-density lipoproteins within individuals. The lipoprotein class most characteristic for an individual was the 4-0s(f) or HDL(2) fraction.
No takes yet. Share an insight, caveat, or question.
Barclay et al. (1965) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More from Biochemical Journal