Key result
Each 1-unit increase in the triglyceride-glucose index was associated with a 2.19-fold higher risk of in-hospital all-cause mortality among critically ill patients.
Why the study?
The relationship between the triglyceride-glucose index, a surrogate of insulin resistance, and all-cause mortality in ICU patients remains unknown.
Does a higher Triglyceride-glucose (TyG) index predict increased all-cause mortality in critically ill ICU patients?
Cohort (n=3,026)
No
Does a higher Triglyceride-glucose (TyG) index predict increased all-cause mortality in critically ill ICU patients?
Effect estimate: HR 2.19 (95% CI 1.59-3.03)
p-value: p=<0.001
The Triglyceride-glucose (TyG) index is a strong, independent predictor of all-cause mortality in critically ill patients, suggesting its utility as a simple biomarker for identifying high-risk ICU patients.
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Higher TyG index may identify high-risk ICU patients; leaves open whether it improves risk stratification or outcomes.
Liao et al. (2022) conducted a cohort in Critically ill patients (n=3,026). Triglyceride-glucose (TyG) index was evaluated on In-hospital all-cause mortality (HR 2.19, 95% CI 1.59-3.03, p=<0.001). Each 1-unit increase in the triglyceride-glucose index was associated with a 2.19-fold higher risk of in-hospital all-cause mortality among critically ill patients.
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