Key result
Oral anticoagulants were inadequately utilized in 52.8% of high-risk patients with nonvalvular atrial fibrillation, while proper administration during follow-up resulted in a 3.8% annual incidence of cerebrovascular accidents.
Why the study?
What is the rate of appropriate oral anticoagulant use and subsequent cerebrovascular events in patients with nonvalvular atrial fibrillation?
Observational (n=255)
No
What is the rate of appropriate oral anticoagulant use and subsequent cerebrovascular events in patients with nonvalvular atrial fibrillation?
Absolute Event Rate: 3.8% vs 4.5%
Oral anticoagulants are significantly underused in Italian patients with nonvalvular atrial fibrillation, often without clear bleeding contraindications.
Authors
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Persistent underuse of oral anticoagulants in high-risk nonvalvular AF warrants caution; leaves open optimal strategies to enhance appropriate prescribing.
Ferro et al. (2007) conducted an observational in Nonvalvular atrial fibrillation (n=255). Oral anticoagulants vs. Aspirin was evaluated on Annual incidence of cerebrovascular accidents. Oral anticoagulants were inadequately utilized in 52.8% of high-risk patients with nonvalvular atrial fibrillation, while proper administration during follow-up resulted in a 3.8% annual incidence of cerebrovascular accidents.
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