Observational study finds daytime predominance of intracerebral hemorrhage onset in stroke patients, suggesting daily blood pressure cycles contribute to hemorrhage risk.
We studied the time of onset of spontaneous supratentorial intracerebral hemorrhage, with regard to the time of the day and the season, in 157 consecutive patients. Intracerebral hemorrhage occurred more often during the daytime (6 a.m. – 6 p.m.) than during the evening and night (p < 0.01). No seasonal variation was found in the group as a whole, in subgroups with a history of hypertension (n = 59), or with age below or above 65 years. A rise in blood pressure contributes to the pathogenesis of intracerebral hemorrhage, but is not a necessary factor.
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Franke et al. (1992) studied this question.
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