Key result
Female cardiac patients had a significantly higher prevalence of severe depression compared to male patients (61.4% vs 50.7%), an association mediated by factors including PTSD and resilience.
Why the study?
Little is known about characteristics that differentiate men and women with CHD and comorbid depression, and whether these factors mediate gender effects on depression.
Does female gender increase the risk of depression in cardiovascular disease patients, and what factors mediate this effect?
Cross-Sectional (n=1,022)
Yes
Does female gender increase the risk of depression in cardiovascular disease patients, and what factors mediate this effect?
Absolute Event Rate: 61.4% vs 50.7%
p-value: p=0.003
Female cardiac patients have a higher prevalence of severe depression than males, an effect entirely mediated by psychosocial and lifestyle factors such as PTSD, resilience, and physical activity rather than a direct effect of gender.
No takes yet. Share an insight, caveat, or question.
May warrant targeted depression screening in female cardiac patients; leaves open direct versus mediated effects of gender.
Allabadi et al. (2019) conducted a cross-sectional in Cardiovascular disease (n=1,022). Female gender vs. Male gender was evaluated on Severe depression (CDS > 100) (p=0.003). Female cardiac patients had a significantly higher prevalence of severe depression compared to male patients (61.4% vs 50.7%), an association mediated by factors including PTSD and resilience.
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