Why the study?
Does IV phentolamine improve septal movement on echocardiogram in a patient with coronary artery disease?
Does IV phentolamine improve septal movement on echocardiogram in a patient with coronary artery disease?
IV phentolamine may be useful as an agent to detect reversible areas of left ventricular wall motion abnormalities in patients with coronary artery disease.
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Phentolamine may identify reversible septal dysfunction in CAD; this single case leaves open diagnostic utility.
Left ventricular wall motion abnormalities are commonly seen in coronary artery disease patients. The differentiation between reversibly ischemic areas an irreversibly damaged areas is 1 was of predicting which patient might gain improved ventricular function from surgical correction. One patient with coronary artery disease is presented here who showed poor septal movement on his echocardiogram. After the IV administration of phentolamine, the septal movement became normal. Thus, phentolamine should be considered as an agent that can detect reversible areas of wall motion abnormalities.
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Gould et al. (1982) studied this question.
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