Why the study?
Does sublingual nitroglycerin improve left ventricular wall motion abnormalities and ejection fraction in patients with coronary artery disease?
Population
25 patients, including 16 with coronary artery disease, 6 with no evidence of heart disease, and 3 with…
Comparison
0.4 mg of sublingual nitroglycerin vs Baseline (prior to administration)
Design
Case_series
Follow-up
6 minutes
Authors
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Should not yet change practice in CAD; leaves open whether nitroglycerin-augmented ventriculography identifies reversible ischemia.
Does sublingual nitroglycerin improve left ventricular wall motion abnormalities and ejection fraction in patients with coronary artery disease?
Sublingual nitroglycerin can improve left ventricular wall motion abnormalities and ejection fraction in a subset of patients with coronary artery disease, suggesting ventriculography before and after administration may help identify reversible ischemia.
McAnulty et al. (1975) studied this question.
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