March 1, 1975Angiology
Effect of Sublingual Nitroglycerin On Ejection Fraction and Left Ventricular Asynergy in Coronary Disease
Why the study?
Does sublingual nitroglycerin improve ejection fraction and left ventricular asynergy in patients with coronary disease?
Population
19 patients with coronary disease
Comparison
Sublingual nitroglycerin vs Baseline
Design
Case_series
Follow-up
Immediate (after sublingual nitroglycerin administration)
Authors
Discussion
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Member takes
Implication
May identify viable myocardium on ventriculography; hypothesis-generating case report requiring prospective validation.
Structured PICO
Does sublingual nitroglycerin improve ejection fraction and left ventricular asynergy in patients with coronary disease?
P
Population
19 patients with coronary disease
I
Intervention
Sublingual nitroglycerin
C
Comparator
Baseline (before sublingual nitroglycerin administration)
O
Outcome
Change in ejection fraction and left ventricular asynergy (hypokinesis, akinesis, dyskinesis)surrogate
Left ventriculography performed before and after sublingual nitroglycerin can help predict viable areas of ischemic myocardium by demonstrating improvements in ejection fraction and hypokinesis.
Cite This Study
Khemka et al. (1975) studied this question.