Key result
Systemic inflammatory response syndrome at presentation in STEMI patients was associated with increased 90-day death, shock, heart failure, or stroke (31.0% vs 16.7%; adjusted HR 1.78; p<0.001).
Why the study?
Does the presence of systemic inflammatory response syndrome (SIRS) increase the risk of death, shock, heart failure, or stroke in patients with ST-elevation myocardial infarction?
Cohort (n=1,903)
Yes
Does the presence of systemic inflammatory response syndrome (SIRS) increase the risk of death, shock, heart failure, or stroke in patients with ST-elevation myocardial infarction?
Answers are grounded in this paper and cite their sources.
The presence of systemic inflammatory response syndrome (SIRS) at presentation or 24 hours is independently associated with worse 90-day clinical outcomes in patients with STEMI.
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Diepen et al. (2013) conducted a cohort in ST-elevation myocardial infarction (n=1,903). Systemic inflammatory response syndrome vs. No systemic inflammatory response syndrome was evaluated on 90-day prevalence of death, shock, heart failure, or stroke (adjusted HR 1.78, 95% CI 1.35-2.34, p=<0.001). Systemic inflammatory response syndrome at presentation in STEMI patients was associated with increased 90-day death, shock, heart failure, or stroke (31.0% vs 16.7%; adjusted HR 1.78; p<0.001).
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