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April 1, 1990Human Gene Therapy

Long-Term Expression of Human Adenosine Deaminase in Mice after Transplantation of Bone Marrow Infected with Amphotropic Retroviral Vectors

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Authors

WOWilliam OsborneHeartlands HospitalRHRandy A. HockUniversity of WürzburgMKMichael KalekoCenter for Biologics Evaluation and Research

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Cite This Study

Osborne et al. (1990) studied this question.

synapsesocial.com/papers/6a1d85c97328fa9a742fa001https://doi.org/10.1089/hum.1990.1.1-31
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.1989 · 148 citations
  2. 2Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines1989 · 112 citations
  3. 3Canine model for gene therapy: inefficient gene expression in dogs reconstituted with autologous marrow infected with retroviral vectors1988 · 95 citations
  4. 4Canine model for gene therapy: inefficient gene expression in dogs reconstituted with autologous marrow infected with retroviral vectors1988 · 72 citations
  5. 5Expression of human adenosine deaminase in murine hematopoietic cells.1988 · 110 citations