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August 1, 2010BMJ Quality & Safety

Paediatric dosing errors before and after electronic prescribing

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Authors

YJYogini JaniDharmsinh Desai UniversityNBNick BarberMcPin FoundationIWIan Chi Kei WongMacau University of Science and Technology

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Implication

Pre-post comparative study reveals reduced pediatric dosing errors after electronic prescribing implementation, indicating improved medication safety in hospital care.

Key Points

  • To compare the incidence and clinical severity rating of dose prescribing errors before and after the introduction of a commercial electronic prescribing system at a tertiary children's hospital.
  • Conducted prescription reviews to identify dose errors across outpatient, inpatient, and discharge orders before (N=3,939 prescribed items) and after (N=4,784 prescribed items) electronic prescribing implementation.
  • Assigned error severity using a validated scoring tool evaluated by five judges, using the mean score as an index of severity.
  • Total dose prescribing errors dropped from 88 of 3,939 items (2.2%) pre-implementation to 57 of 4,784 items (1.2%) post-implementation, an absolute reduction of 1.0% (95% CI of difference, -1.6% to -0.5%; p < 0.001).
  • Minor severity errors decreased from 35/3,939 (0.89%) to 21/4,784 (0.44%; 95% CI, -0.8% to -0.11%; p = 0.009), and moderate severity errors decreased from 46/3,939 (1.17%) to 33/4,784 (0.69%; 95% CI, -0.91% to -0.08%; p = 0.019).
  • Severe outcome errors declined from 7/3,939 (0.18%) pre-implementation to 3/4,784 (0.06%) post-implementation, but the change did not achieve statistical significance (95% CI, -0.31% to +0.04%; p = 0.11).

Cite This Study

Jani et al. (2010) studied this question.

synapsesocial.com/papers/6a1d8fcacc9f7df1b705a126https://doi.org/10.1136/qshc.2009.033068
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