Impact of sedentary behavior and physical activity on stroke risk in a cohort of patients with silent brain infarction

Figures

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  Fig. 1. Study flow diagram. Note: SBI, Silent Brain Infarction.

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  Fig. 2. Comparison of ST and physical activity levels between groups. Note: (A) Comparison of Total Sedentary Time Between Two Groups; (B) Comparison of LPA Time Between Two Groups; (C) Comparison of MVPA Between Two Groups; (D) Comparison of TPA Between Two Groups LPA, Low Intensity Physical Activity; MVPA, Moderate-to-Vigorous Intensity Physical Activity; TPA, Total Intensity Physical Activity. *P < 0.05, **P < 0.001.

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  Fig. 3. Dose-response of ST and risk of stroke in SBI patients. Note: adjusted covariates include age, education, smoking, drinking history, hypertension, diabetes, dyslipidemia, cardiovascular disease, SBP, infarct volume, number and location of infarcts, WMH volume and cerebral white matter lesions; medication use (cardiac medications, antihypertensive drugs). HR hazard ratio and CI confidence interval, SBI Silent Brain Infarction.

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  Fig. 4. Joint association of ST and MVPA with stroke risk in SBI patients. Note: (A) Joint association of ST and MVPA with stroke risk in SBI patients in raw model between groups; (B) Joint association of ST and MVPA with stroke risk in SBI patients in adjusted models (age, education, smoking, drinking history, hypertension, diabetes, dyslipidemia, cardiovascular disease, SBP, infarct volume, number and location of infarcts, WMH volume and cerebral white matter lesions; medication use (cardiac medications, antihypertensive drugs); HR hazard ratio and CI confidence interval, ST sedentary time, MVPA Moderate-to-Vigorous Intensity Physical Activity, h/day, hour/day, min/wk minute/week.