Key result
Thomas Pickering's seminal work on white-coat and masked hypertension, diurnal BP variability, and self-measured BP laid the foundation for modern risk stratification algorithms and clinical practice.
This review honors Thomas Pickering's legacy by summarizing his foundational research on automated blood pressure measurement and its translation into modern clinical practice.
Reinforces out-of-office BP monitoring in risk stratification; extends Pickering's foundational insights to current guidelines and future studies.
Thomas G. Pickering spent most of his scientific career in carrying out research on clinical hypertension and blood pressure (BP) measurement. In our review of Pickering's seminal work, we first focused on white-coat hypertension and masked hypertension, two terms that he had introduced. Next, we highlighted the early publications of Pickering on diurnal BP variability and on the clinical application of self-measured BP. Pickering's work inspired many investigators worldwide and constituted a solid basis for further research. Pickering's original ideas led to algorithms for risk stratification involving white-coat hypertension and masked hypertension, diurnal BP variability, and self-measured BP. Recent studies validated Pickering's observations in terms of cardiovascular outcome and bridged the path from concept to application in clinical practice.
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Stolarz‐Skrzypek et al. (2010) conducted a review in Hypertension. Automated blood pressure measurement was evaluated. Thomas Pickering's seminal work on white-coat and masked hypertension, diurnal BP variability, and self-measured BP laid the foundation for modern risk stratification algorithms and clinical practice.
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