Key result
Coronary artery bypass grafting significantly improved mean ejection fraction from 29.2% preoperatively to 33.8% at 12 months in patients with poor left ventricular function.
Why the study?
To compare preoperative and postoperative ventricular functions in patients with ventricular dysfunction undergoing CABG and evaluate whether there was significant functional improvement.
Does coronary artery bypass grafting improve ventricular function in patients with coronary artery disease and poor left ventricular function?
Observational (n=30)
No
Does coronary artery bypass grafting improve ventricular function in patients with coronary artery disease and poor left ventricular function?
Absolute Event Rate: 33.8% vs 29.23%
p-value: p=0.004
Coronary artery bypass grafting significantly improves global ventricular function, left ventricular end-diastolic pressure, and functional capacity in patients with ischemic heart disease and severe left ventricular dysfunction.
CABG may support EF gains in severe LV dysfunction; hypothesis-generating and leaves open randomized confirmation before practice change.
Objectives: The aim of the present study was to compare preoperative / postoperative ventricular functions of patients with ventricular dysfunction who were planned for coronary artery bypass grafting (CABG) using echocardiography and angiography, and to evaluate whether there was a significant improvement in ventricular function.Methods: This prospective study included 30 patients with poor ventricular function who had undergone CABG at the Cardiovascular Surgery Clinics of Bursa Yüksek Ihtisas Hospital. The patients' ventricular functions were compared preoperatively and postoperatively at the 2nd, 6th and 12th months.Results: Of the patients, 28 were males, and the mean age was 60.1 ± 8 years (range 39-71). In these cases, functional capacity improved within the early postoperative period, and global ventricular functions improved within the postoperative first year. The improvement in ejection fraction results was statistically significant at 6 months and 12 months (p < 0.05). A significant decrease was observed in left ventricular enddiastolic pressures within one year (p < 0.001). For the performance score, improvement was significant from the 2nd month (p < 0.05). Conclusions: Our findings show that CABG improves ventricular function in terms of EF, PS, LVEDP and NYHA classification. In conclusion, we consider that CABG is a significantly effective option in patients with poor ventricular function.
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Ozturk et al. (2019) conducted an observational in Coronary artery disease with poor left ventricular function (n=30). Coronary artery bypass grafting (CABG) vs. Preoperative baseline was evaluated on Mean ejection fraction (EF) at 12 months (p=0.004). Coronary artery bypass grafting significantly improved mean ejection fraction from 29.2% preoperatively to 33.8% at 12 months in patients with poor left ventricular function.
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