What does this research mean for the field?

Ventricular pacing effectively abolishes syncope and prevents paroxysmal tachycardia in patients with chronic sinoatrial disease, whereas drug therapy alone is generally unsatisfactory. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To determine the incidence, clinical characteristics, and long-term outcomes of different management approaches in patients with chronic sinoatrial disease.

June 1, 1974HeartOpen Access

Prospective study on the occurrence and management of chronic sinoatrial disease, with follow-up.

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Why the study?

Does pacemaker implantation prevent syncope and paroxysmal tachycardia in patients with chronic sinoatrial disease compared to medical or no therapy?

Population

51 patients with chronic sinoatrial disease

Comparison

Pacemaker implantation (ventricular pacing) (n=23) vs Medical or no therapy (n=28)

Design

Cohort

Follow-up

average 5 years

Authors

RRR. RoksethInstitute of Cardiology LHLiv HatleCardiac Imaging

Discussion

Member takes

Implication

Supports pacing consideration in sinoatrial disease but should not change practice; leaves open randomized confirmation versus drugs.

Key Points

To determine the incidence, clinical characteristics, and long-term outcomes of different management approaches in patients with chronic sinoatrial disease.
Prospective cohort study evaluating 51 patients with chronic sinoatrial disease compared against 98 patients presenting with atrioventricular block.
Patients received either ventricular pacemaker implantation (N=23) or medical/conservative management (N=28) and were followed for an average of 5 years.
Sinoatrial disease represented a 34% relative incidence compared to atrioventricular block, with approximately 60% presenting with paroxysmal tachyarrhythmias and 20% reporting past rheumatic fever.
Ventricular pacing abolished syncope and prevented paroxysmal tachycardia in 23 patients without the routine need for additional pharmacological therapy.
Medical therapy alone proved broadly unsatisfactory, though low-dose digitalis helped 6 patients with predominant tachycardia and oral isoprenaline prevented syncope in 5 patients with isolated bradycardia.

Structured PICO

Does pacemaker implantation prevent syncope and paroxysmal tachycardia in patients with chronic sinoatrial disease compared to medical or no therapy?

Population

51 patients with chronic sinoatrial disease

Intervention

Pacemaker implantation (ventricular pacing) (n=23)

Comparator

Medical or no therapy (n=28)

Outcome

Prevention of syncope and paroxysmal tachycardia

Cite This Study

Rokseth et al. (1974) studied this question.

synapsesocial.com/papers/6a1d9b8533e2df9c962fc62c https://doi.org/10.1136/hrt.36.6.582

Topics

Heart failure HFrEF treatment Atrial fibrillation Persistent AF management

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Prospective study on the occurrence and management of chronic sinoatrial disease, with follow-up.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Prospective study on the occurrence and management of chronic sinoatrial disease, with follow-up.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider