Key result
MINOCA was associated with smaller myocardial infarct size, lower peak cardiac troponin, and greater ejection fraction compared to MICAD (all P<0.005), with similar 30-day readmission rates.
Why the study?
Few studies have examined CAD extent, MI size and type, and discharge treatment differences between MINOCA and MICAD, or explored sex-specific MINOCA attributes.
Do patients with MINOCA have different MI size, ejection fraction, and clinical characteristics compared to patients with MICAD?
Observational (n=1,698)
No
Do patients with MINOCA have different MI size, ejection fraction, and clinical characteristics compared to patients with MICAD?
p-value: p=<0.005
MINOCA patients have smaller infarct sizes and higher ejection fractions than MICAD patients but are less likely to receive guideline-directed medical therapy despite similar 30-day readmission rates.
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MINOCA may warrant distinct risk stratification from MICAD; leaves open whether therapy intensity should differ in this observational cohort.
Alkhawam et al. (2021) conducted an observational in Myocardial infarction in nonobstructive coronary artery disease (MINOCA) (n=1,698). MINOCA vs. MICAD was evaluated on MI size, ejection fraction, and 30-day re-admission rates (p=<0.005). MINOCA was associated with smaller myocardial infarct size, lower peak cardiac troponin, and greater ejection fraction compared to MICAD (all P<0.005), with similar 30-day readmission rates.
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