Key result
Hypertension may result from early developmental vascular mechanisms that direct blood pressure toward the higher percentiles of the Gaussian distribution curve from birth onward.
The authors propose that hypertension originates from early developmental vascular mechanisms affecting mean arterial pressure and pulse pressure tracking from birth.
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Should not change clinical practice; hypothesis-generating for developmental vascular origins of hypertension and requires prospective validation.
Safar et al. (2005) conducted a review in Hypertension. Hypertension may result from early developmental vascular mechanisms that direct blood pressure toward the higher percentiles of the Gaussian distribution curve from birth onward.
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