Key result
Pediatric intervention during adolescence, including lifestyle changes and lipid-lowering medications to achieve an LDLc <110 mg/dl, may prevent the progression of atherosclerosis into adulthood.
Pediatricians have a critical opportunity to prevent adult atherosclerotic cardiovascular disease by aggressively managing risk factors and targeting LDLc <110 mg/dl in adolescents.
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May support targeting LDLc <110 mg/dl in adolescents; leaves open need for prospective trials to confirm outcomes.
Schade et al. (2018) conducted a review in Atherosclerosis. Lipid-lowering therapy (lifestyle and medications) was evaluated. Pediatric intervention during adolescence, including lifestyle changes and lipid-lowering medications to achieve an LDLc <110 mg/dl, may prevent the progression of atherosclerosis into adulthood.
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