What does this research mean for the field?

Waist-hip ratio in women and body mass index in men are the primary predictors of changes in HDL2 cholesterol levels in response to dietary fat and cholesterol supplementation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 1, 1995Arteriosclerosis Thrombosis and Vascular Biology

Body Fat Distribution Is a Determinant of the High-Density Lipoprotein Response to Dietary Fat and Cholesterol in Women

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Why the study?

Does body fat distribution and gender influence the plasma lipid response to dietary fat and cholesterol in adults?

Population

120 adults selected so that overall men and women had a similar mean age, LDL cholesterol, and body mass index

Comparison

Liquid supplement containing 31 to 40 g fat and… vs Fat-free liquid supplement for 3 weeks

Follow-up

3 weeks per supplement phase

Authors

PCPeter CliftonGeneral / Preventive / Lipids MAMavis AbbeyCommonwealth Scientific and Industrial Research Organisation MNM. NoakesCommonwealth Scientific and Industrial Research Organisation

Discussion

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Implication

Body fat distribution may predict sex-specific HDL2 responses to diet; hypothesis-generating and should not yet inform clinical recommendations.

Structured PICO

Does body fat distribution and gender influence the plasma lipid response to dietary fat and cholesterol in adults?

Population

120 adults (67 women, 53 men) selected so that overall men and women had a similar mean age, LDL cholesterol, and body mass index

Intervention

Liquid supplement containing 31 to 40 g fat and 650 to 845 mg cholesterol for 3 weeks (following a 2-week low-fat period)

Comparator

Fat-free liquid supplement for 3 weeks

Outcome

Changes in plasma lipids and lipoproteins (specifically HDL and LDL cholesterol)surrogate

Body fat distribution, specifically waist-hip ratio in women and body mass index in men, is a significant determinant of the HDL2 cholesterol response to dietary fat and cholesterol.

Cite This Study

Clifton et al. (1995) studied this question.

synapsesocial.com/papers/6a1deeb48b32c80b5460361b https://doi.org/10.1161/01.atv.15.8.1070

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Implication

Body fat distribution may predict sex-specific HDL2 responses to diet; hypothesis-generating and should not yet inform clinical recommendations.

Body Fat Distribution Is a Determinant of the High-Density Lipoprotein Response to Dietary Fat and Cholesterol in Women

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Body Fat Distribution Is a Determinant of the High-Density Lipoprotein Response to Dietary Fat and Cholesterol in Women

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider