Identifies a novel fast myosin heavy chain isoform (MHCIId) in adult rat skeletal muscle that is responsive to chronic stimulation.
Novel MHCIId isoform responsive to stimulation in rats; extends rodent muscle biology but leaves open human applicability.
A new fast myosin heavy chain isoform was electrophoretically detected in adult rat skeletal muscles. It was present at high levels in diaphragm and, therefore, designated as MHCIId. Appreciable amounts of MHCIId were detected in tongue musculature, the extraocular muscles, and in the deep red portions of various fast muscles. Its concentration in fast-twitch muscle was greatly increased by chronic stimulation.
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BÄR et al. (1988) studied this question.
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