Why the study?
Does carotid endarterectomy prevent stroke in patients with varying degrees of symptomatic and asymptomatic carotid stenosis compared to medical care alone?
Does carotid endarterectomy prevent stroke in patients with varying degrees of symptomatic and asymptomatic carotid stenosis compared to medical care alone?
Carotid endarterectomy provides clear benefit for symptomatic patients with severe stenosis and low operative risk, but its value in asymptomatic patients is highly questionable due to a high number needed to treat.
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Supports endarterectomy in symptomatic severe stenosis with low risk; leaves open net benefit in asymptomatic patients given high NNT.
Barnett et al. (2001) studied this question.
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