Why the study?
The clinical characteristics and pregnancy outcomes of pregnant women with pulmonary arterial hypertension required investigation across different disease severities.
Does the severity of pulmonary arterial hypertension affect pregnancy outcomes in pregnant women?
Does the severity of pulmonary arterial hypertension affect pregnancy outcomes in pregnant women?
Higher pulmonary artery systolic blood pressure is associated with worse pregnancy outcomes and prognosis in pregnant women with pulmonary arterial hypertension.
Answers are grounded in this paper and cite their sources.
Supports risk stratification by PAP severity in pregnant PAH patients; leaves open need for prospective validation before guiding care.
OBJECTIVES: To investigate the clinical situation and pregnancy outcome of pregnant women with pulmonary arterial hypertension (PAH). METHODS: A retrospective analysis was conducted on 125 pregnant women with varying degrees of PAH who were treated in the Department of Obstetrics and Gynecology of the First Affiliated Hospital of the University of Science and Technology between January 2016 and January 2023. The patients were divided into the mild group (58 cases), the moderate group (42 cases), and the severe group (25 cases) based on the pulmonary artery systolic blood pressure (PASBP) measurements. Mild was considered as PASBP 30-49 mmHg, moderate as PASBP 50-79 mmHg, and severe as PASBP ≥80 mmHg. The clinical data, cardiac function grade, etiology, and pregnancy outcome of the pregnant women with different degrees of severity of PASBP were analyzed. CONCLUSIONS: The higher the pulmonary artery pressure, the worse the prognosis and outcome in pregnant patients with severe PAH.
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Shi et al. (2025) studied this question.
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